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Abstract

Dyke-Davidoff-Masson Syndrome (DDMS) is a rare neurological condition characterized by unilateral cerebral atrophy, frequently associated with motor manifestations and epilepsy. Although its correlation with psychiatric disorders has been scarcely studied, isolated cases of schizophrenia in patients with DDMS have been documented. This article presents four clinical cases of pediatric patients diagnosed with DDMS, three of whom had epilepsy, and all exhibited manifestations compatible with schizophrenia. The possible neurobiological relationship between the structural brain alterations in DDMS and the development of psychosis is discussed, emphasizing the importance of an interdisciplinary approach for diagnosis and management. This report aims to contribute additional evidence regarding the association between DDMS and schizophrenia and to highlight the need for long-term neuropsychiatric follow-up.

 

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Keywords

Dyke-Davidoff-Masson, schizophrenia, epilepsy, cerebral hemiatrophy, neuroimaging

References

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Section
Case Reports

How to Cite

Beyond hemiatrophy: Catatonic schizophrenic manifestations in patients with Dyke-Davidoff-Masson syndrome. (2026). Revista Chilena De Neurocirugía, 51(2), 92-98. https://doi.org/10.36593/yqjjwf37