##plugins.themes.bootstrap3.article.main##

Abstract

Myeloid Sarcoma (MS), also known as Granulocytic Sarcoma, first described in 1811, is defined as an extramedullary tumor composed of myeloid hematological cells, which is associated with patients with previous hematological disorders. A case is presented of a 32-year-old male patient with a history of Acute Myeloid Leukemia (AML) in remission, who presents with a clinical history of 3 weeks of evolution of radicular pain in the right L5 territory, associated with acute bladder dysfunction of 24 hours duration. Imaging is performed, revealing extensive occupation of the lumbar and sacral canal, as well as soft tissues. Given this, emergency surgery is performed due to a diagnosis of cauda equina. Biopsy results indicate Myeloid Sarcoma.

##plugins.themes.bootstrap3.article.details##

Keywords

Myeloid sarcoma, granulocytic, acute myeloid leukemia

References

- García E, Yebra E, Rodríguez R, Agud J, Riaza R, Valle B, Burgos F. Compresión medular por sarcoma granulocítico primario. Revista colombiana de cancerología. Doi: 10.1016/j.rccan.2015.03.003. DOI: https://doi.org/10.1016/j.rccan.2015.03.003

- WHO classification of tumours of haematopoietic and lymphoid tissues I edited by Steven H. Swerdlow, Elias Campo, Nancy Lee Harris, Elaine S. Jaffe, Stefano A. Pileri, Harald Stein, Jurgen Thiele. - Revised 4th edition.

- Avni B, Koren-Michowitz M. Myeloid sarcoma: current approach and therapeutic options. Ther Adv Hematol. 2011 Oct;2(5):309-16. doi: 10.1177/2040620711410774. PMID: 23556098; PMCID: PMC3573418 DOI: https://doi.org/10.1177/2040620711410774

- Hu X, Shahab I, Lieberman IH. Spinal Myeloid Sarcoma "Chloroma" Presenting as Cervical Radiculopathy: Case Report. Global Spine J. 2015 Jun;5(3):241-6. doi: 10.1055/s-0035-1549433. PMID: 26131394; PMCID: PMC4472287. DOI: https://doi.org/10.1055/s-0035-1549433

- Chamberlain MC, Tredway TL. Adult primary intradural spinal cord tumors: a review. Curr Neurol Neurosci Rep. 2011 Jun;11(3):320-8. doi: 10.1007/s11910-011-0190-2. PMID: 21327734. DOI: https://doi.org/10.1007/s11910-011-0190-2

- Meyer, H. J., & Surov, A. (2020).Myeloides Sarkom. RöFo – Fortschritte Auf Dem Gebiet Der Röntgenstrahlen Und Der Bildgebenden Verfahren.doi:10.1055/a-1150-8131. DOI: https://doi.org/10.1055/a-1150-8131

- Quaile A. Cauda equina syndrome-the questions. Int Orthop. 2019 Apr;43(4):957-961. doi: 10.1007/s00264-018-4208-0. Epub 2018 Oct 29. PMID: 30374638. DOI: https://doi.org/10.1007/s00264-018-4208-0

- Meyer HJ, Beimler M, Borte G, Pönisch W, Surov A. Radiological and clinical patterns of myeloid sarcoma. Radiol Oncol. 2019 Mar 14;53(2):213-218. doi: 10.2478/raon-2019-0014. PMID: 30893056; PMCID: PMC6572499 DOI: https://doi.org/10.2478/raon-2019-0014

- Stölzel F, Röllig C, Radke J, Mohr B, Platzbecker U, Bornhäuser M, Paulus T, Ehninger G, Zöphel K, Schaich M. ¹⁸F-FDG-PET/CT for detection of extramedullary acute myeloid leukemia. Haematologica. 2011 Oct;96(10):1552-6. doi: 10.3324/haematol.2011.045047. Epub 2011 Jun 17. PMID: 21685468; PMCID: PMC3186319. DOI: https://doi.org/10.3324/haematol.2011.045047

- Pileri SA, Ascani S, Cox MC, Campidelli C, Bacci F, Piccioli M, Piccaluga PP, Agostinelli C, Asioli S, Novero D, Bisceglia M, Ponzoni M, Gentile A, Rinaldi P, Franco V, Vincelli D, Pileri A Jr, Gasbarra R, Falini B, Zinzani PL, Baccarani M. Myeloid sarcoma: clinico-pathologic, phenotypic and cytogenetic analysis of 92 adult patients. Leukemia. 2007 Feb;21(2):340-50. doi: 10.1038/sj.leu.2404491. Epub 2006 Dec 14. PMID: 17170724 DOI: https://doi.org/10.1038/sj.leu.2404491

- Hogan WB, Kuris EO, Durand WM, Eltorai AEM, Daniels AH. Timing of Surgical Decompression for Cauda Equina Syndrome. World Neurosurg. 2019 Dec;132:e732-e738. doi: 10.1016/j.wneu.2019.08.030. Epub 2019 Aug 12. PMID: 31415897 DOI: https://doi.org/10.1016/j.wneu.2019.08.030

- Hussain I, Parker WE, Barzilai O, Bilsky MH. Surgical Management of Intramedullary Spinal Cord Tumors. Neurosurg Clin N Am. 2020 Apr;31(2):237-249. doi: 10.1016/j.nec.2019.12.004. Epub 2020 Jan 31. PMID: 32147015. DOI: https://doi.org/10.1016/j.nec.2019.12.004

- Shahin, O. A., & Ravandi, F.(2020). Myeloid sarcoma. Current Opinion in Hematology,1. doi:10.1097/moh.00000000000005 DOI: https://doi.org/10.1097/MOH.0000000000000571

Section
Case Reports

How to Cite

Spinal Sarcoma Myeloid: Case report and literature review. (2023). Revista Chilena De Neurocirugía, 49(1), 38-42. https://doi.org/10.36593/revchilneurocir.v49i1.347

Most read articles by the same author(s)