Hemorragia intracraneal secundario a déficit de factor V. A propósito de un caso

Abstract

Factor V deficiency is a hemorrhagic disorder that occurs only in 1 case /1million habitants, it: It appears at any age, with special impact on childhood; it can be congenital or acquired, and can be asymptomatic throughout lifetime or debut in each two of both ways: hemorrhagic or the thrombotic variety (Factor V Leyden), by mutation at site of cleavage of protein C to factor V. It does not exist so far available treatment with factor V, so it is based on fresh frozen plasma and platelet units. The present case is a minor infant with central system nervous bleeding as the only sign of the disease, with severe presentation, associated with prolongation of coagulation times, which, after multiple complications, responded satisfactorily to the medical-surgical treatment applied.